Detalhe da pesquisa
1.
Modelling amyotrophic lateral sclerosis in rodents.
Nat Rev Neurosci
; 23(4): 231-251, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35260846
2.
Insights into the pathogenic mechanisms of Chromosome 9 open reading frame 72 (C9orf72) repeat expansions.
J Neurochem
; 138 Suppl 1: 145-62, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27016280
3.
Polyglutamine disease toxicity is regulated by Nemo-like kinase in spinocerebellar ataxia type 1.
J Neurosci
; 33(22): 9328-36, 2013 May 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-23719801
4.
Generation and characterization of monoclonal antibodies against pathologically phosphorylated TDP-43.
PLoS One
; 19(4): e0298080, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38635657
5.
TMEM106B core deposition associates with TDP-43 pathology and is increased in risk SNP carriers for frontotemporal dementia.
Sci Transl Med
; 16(730): eadf9735, 2024 Jan 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38232138
6.
The endolysosomal pathway and ALS/FTD.
Trends Neurosci
; 46(12): 1025-1041, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37827960
7.
Plasma PolyQ-ATXN3 Levels Associate With Cerebellar Degeneration and Behavioral Abnormalities in a New AAV-Based SCA3 Mouse Model.
Front Cell Dev Biol
; 10: 863089, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35386195
8.
Two FTD-ALS genes converge on the endosomal pathway to induce TDP-43 pathology and degeneration.
Science
; 378(6615): 94-99, 2022 10 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36201573
9.
Microglial lysosome dysfunction contributes to white matter pathology and TDP-43 proteinopathy in GRN-associated FTD.
Cell Rep
; 36(8): 109581, 2021 08 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34433069
10.
HDAC6 Interacts With Poly (GA) and Modulates its Accumulation in c9FTD/ALS.
Front Cell Dev Biol
; 9: 809942, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-35096836
11.
Hexanucleotide Repeat Expansions in c9FTD/ALS and SCA36 Confer Selective Patterns of Neurodegeneration In Vivo.
Cell Rep
; 31(5): 107616, 2020 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32375043
12.
Chimeric Peptide Species Contribute to Divergent Dipeptide Repeat Pathology in c9ALS/FTD and SCA36.
Neuron
; 107(2): 292-305.e6, 2020 07 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32375063
13.
Amyotrophic lateral sclerosis - insight into susceptibility.
Nat Rev Neurol
; 18(4): 189-190, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35197579
14.
Nemo-like kinase is a novel regulator of spinal and bulbar muscular atrophy.
Elife
; 4: e08493, 2015 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-26308581
15.
Aggregation formation in the polyglutamine diseases: protection at a cost?
Mol Cells
; 36(3): 185-94, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23794019